The Ga Tech/UGA game's a pretty good analogy. Back in the late 70's early 80's Pitt/PSU was also a bit like FSU/Miami or UF/Miami. Both teams were usually highly ranked, one had much more fan support but both were a solid tv draw. I think one year they had a 1 vs. 2 showdown, or at least both were in the top 5.
If some of the UF folks with clout hadn't supported developeing a program in Tallahassee, FSU wouldn't even exist. The trade off for them palying us was FSU getting hsafted playing 9 straight years at Florida field (or whatever that hellish place was called then) and getting jobbed by the refs pretty badly. Given, UF was out of our league early on, but we also had some teams that were competitive and one year they flat out robbed us with a downright embarassingly crooked out of bounds call that is memorialized in a Tallahasse paper form the time. If a guy is several feet in bounds and you rule him out, that's bs. Yeah, I'm still bitter...
Anyway we still owe some of the UF folks. Many of them I'm sure they they'd suffer from helping a power program develop in Tallahassee, but the fact is UF only began dominating the SEC after Florida already had two elite football programs and Bowden had cemented FSU as a perennial power. I think it can be beneficial to develop a rival power program in state, because kids want in on that rivalry and the high school football in the state probrably starts developing more talent. But at the same time I think you need to be in a state that produces lots of talent on its home turf. I can see why Bama was threatened by UAB. The state of Alabama produces some rgeat talent for its population, but it can probably only support two power programs at once, and they have to be supplemented by talent out of Memphis, Mississippi, Georgia, texas, and Florida. Losing some depth and a start or two to a team like UAB could knock UA or AU down a peg, though Birmingham is more UA territory, so the threat to Bama, and their response, was much greater.
I think Pennsylvania could afford to have Pitt and PSU both as major powers. If they fight for recruits and the national spotlight, kids will want in on that rivalry. They may lose some recruits to each other, but they'll probably start keeping more kids from the region from heading to Michigan, OSU, Virginia Tech, BC, Syracuse, Notre Dame, etc.
I think the blood is so bad between Marshall and WVU, and the culture warp so severe--this isn't gonna be fair, but at the extremes this is WV hillbilles vs. WV snobs--the WV wil never let it happen. In fairness, it's tough enough to recruit well enough to put WV into the top 10. If Marshall snags some of their recruits, it REALLY hurts.
I think the major football regions, like Texas, Florida, California, and the Steel Mill region in Ohio and Pennsylvania, can probably afford to add a power program or two to the mix. They can even add another if it's a Fresno St./Marshall type program (hey, if Randy Moss doesn't flunk out, something's going on). I don't think any other states can afford to add another succesful program though, unless all the schools in that state raid one of the major high school football talent pools (i.e. Colorado teams raiding Texas).
I think Texas football is heading WAY back up. TCU is gonan continue to roll, Tech is a solid top 20 program at this point, and Francione is gonna make A&M top notch again. That means that Big 10 and of the northern Big 12 schools will have to cast a wider net to improve. Oklahoma will still get it's talent, but Michigan may have to continue raiding eastward. I think Pitt entering the Big 10 might at least make more of the Pennsylvania area talent consider choosing one of the two Pennsylvania schools instead of heading to OSU or Michigan. It'd be nice to see Pitt vs. PSU become the Big 10 equivalent of UF vs. Tennessee (although that game is probably headed down in the dumps in favor of the AU/UGA game).